Gadsden is a census-designated place in Richland County, South Carolina, United States. The population was 1,632 at the 2010 census. It is part of the Columbia, South Carolina metropolitan area.The John J. Kaminer House, Magnolia, Oakwood, and Richland Presbyterian Church are listed on the National Register of Historic Places.Gadsden is located at latitude 33.846 North and longitude 80.766 West. The elevation is 148 feet above sea level. According to the U.S. Census Bureau, the CDP has an area of 11.5 square miles, of which 0.008 square miles, or 0.06%, is water. The community is located at the intersection of state highways 48 and 769.